Aldo-keto Reductase 1C3 (AKR1C3) is Expressed in Differentiated Human Epidermis, Affects Keratinocyte Differentiation and is Upregulated in Atopic Dermatitis

Aldo-keto reductase 1C3 (AKR1C3) has been shown to mediate the metabolism of sex hormones and prostaglandin D(2) (PGD(2)), a lipid mediator that promotes skin inflammation in atopic dermatitis (AD). Since both play a role in skin function and pathology, we first sought to investigate the expression...

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Detalles Bibliográficos
Autores principales: Mantel, Alon, Carpenter-Mendini, Amanda, VanBuskirk, JoAnne, De Benedetto, Anna, Beck, Lisa A., Pentland, Alice P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305848/
https://www.ncbi.nlm.nih.gov/pubmed/22170488
http://dx.doi.org/10.1038/jid.2011.412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305848/
https://www.ncbi.nlm.nih.gov/pubmed/22170488
http://dx.doi.org/10.1038/jid.2011.412

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