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Intravenous pharmacokinetics, oral bioavailability, dose proportionality and in situ permeability of anti-malarial lumefantrine in rats

BACKGROUND: Despite the wide spread use of lumefantrine, there is no study reporting the detailed preclinical pharmacokinetics of lumefantrine. For the development of newer anti-malarial combination(s) and selection of better partner drugs, it is long felt need to understand the detailed preclinical...

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Detalles Bibliográficos
Autores principales:	Wahajuddin, Singh, Sheelendra P, Raju, Kanumuri SR, Nafis, Asad, Puri, Sunil K, Jain, Girish K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305926/ https://www.ncbi.nlm.nih.gov/pubmed/21985153 http://dx.doi.org/10.1186/1475-2875-10-293

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