Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

Inhibition of Hedgehog (HH)/GLI signalling in cancer is a promising therapeutic approach. Interactions between HH/GLI and other oncogenic pathways affect the strength and tumourigenicity of HH/GLI. Cooperation of HH/GLI with epidermal growth factor receptor (EGFR) signalling promotes transformation...

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Detalles Bibliográficos
Autores principales: Eberl, Markus, Klingler, Stefan, Mangelberger, Doris, Loipetzberger, Andrea, Damhofer, Helene, Zoidl, Kerstin, Schnidar, Harald, Hache, Hendrik, Bauer, Hans-Christian, Solca, Flavio, Hauser-Kronberger, Cornelia, Ermilov, Alexandre N, Verhaegen, Monique E, Bichakjian, Christopher K, Dlugosz, Andrzej A, Nietfeld, Wilfried, Sibilia, Maria, Lehrach, Hans, Wierling, Christoph, Aberger, Fritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305999/
https://www.ncbi.nlm.nih.gov/pubmed/22294553
http://dx.doi.org/10.1002/emmm.201100201

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