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Combination Therapies in Ophthalmology: Implications for Intravitreal Delivery
Most pathological processes involve complex molecular pathways that can only be modified or blocked by a combination of medications. Combination therapy has become a common practice in medicine. In ophthalmology, this approach has been used effectively to treat bacterial, fungal, proliferative/neopl...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ophthalmic Research Center
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306066/ https://www.ncbi.nlm.nih.gov/pubmed/22454705 |
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author | Peyman, Gholam A. Hosseini, Kamran |
author_facet | Peyman, Gholam A. Hosseini, Kamran |
author_sort | Peyman, Gholam A. |
collection | PubMed |
description | Most pathological processes involve complex molecular pathways that can only be modified or blocked by a combination of medications. Combination therapy has become a common practice in medicine. In ophthalmology, this approach has been used effectively to treat bacterial, fungal, proliferative/neoplastic, and inflammatory eye diseases and vascular proliferation. Combination therapy also encompasses the synergistic effect of electromagnetic radiation and medications. However, combination therapy can augment inherent complications of individual interventions, therefore vigilance is required. Complications of combination therapy include potential incompatibility among compounds and tissue toxicity. Understanding these effects will assist the ophthalmologist in his decision to maximize the benefits of combination therapy while avoiding an unfavorable outcome. |
format | Online Article Text |
id | pubmed-3306066 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Ophthalmic Research Center |
record_format | MEDLINE/PubMed |
spelling | pubmed-33060662012-03-27 Combination Therapies in Ophthalmology: Implications for Intravitreal Delivery Peyman, Gholam A. Hosseini, Kamran J Ophthalmic Vis Res Review Article Most pathological processes involve complex molecular pathways that can only be modified or blocked by a combination of medications. Combination therapy has become a common practice in medicine. In ophthalmology, this approach has been used effectively to treat bacterial, fungal, proliferative/neoplastic, and inflammatory eye diseases and vascular proliferation. Combination therapy also encompasses the synergistic effect of electromagnetic radiation and medications. However, combination therapy can augment inherent complications of individual interventions, therefore vigilance is required. Complications of combination therapy include potential incompatibility among compounds and tissue toxicity. Understanding these effects will assist the ophthalmologist in his decision to maximize the benefits of combination therapy while avoiding an unfavorable outcome. Ophthalmic Research Center 2011-01 /pmc/articles/PMC3306066/ /pubmed/22454705 Text en http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Peyman, Gholam A. Hosseini, Kamran Combination Therapies in Ophthalmology: Implications for Intravitreal Delivery |
title | Combination Therapies in Ophthalmology: Implications for Intravitreal Delivery |
title_full | Combination Therapies in Ophthalmology: Implications for Intravitreal Delivery |
title_fullStr | Combination Therapies in Ophthalmology: Implications for Intravitreal Delivery |
title_full_unstemmed | Combination Therapies in Ophthalmology: Implications for Intravitreal Delivery |
title_short | Combination Therapies in Ophthalmology: Implications for Intravitreal Delivery |
title_sort | combination therapies in ophthalmology: implications for intravitreal delivery |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306066/ https://www.ncbi.nlm.nih.gov/pubmed/22454705 |
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