in vivo protein trapping produces a functional expression codex of the vertebrate proteome

We describe a conditional in vivo protein trap mutagenesis system that reveals spatio-temporal protein expression dynamics and assesses gene function in the vertebrate Danio rerio. Integration of pGBT-RP2 (RP2), a gene-breaking transposon containing a protein trap, efficiently disrupts gene expressi...

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Detalles Bibliográficos
Autores principales: Clark, Karl J., Balciunas, Darius, Pogoda, Hans-Martin, Ding, Yonghe, Westcot, Stephanie E., Bedell, Victoria M., Greenwood, Tammy M., Urban, Mark D., Skuster, Kimberly J., Petzold, Andrew M., Ni, Jun, Nielsen, Aubrey, Patowary, Ashok, Scaria, Vinod, Sivasubbu, Sridhar, Xu, Xiaolei, Hammerschmidt, Matthias, Ekker, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306164/
https://www.ncbi.nlm.nih.gov/pubmed/21552255
http://dx.doi.org/10.1038/nmeth.1606

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