Cargando…
Expression and Characterization of Drosophila Signal Peptide Peptidase-Like (sppL), a Gene That Encodes an Intramembrane Protease
Intramembrane proteases of the Signal Peptide Peptidase (SPP) family play important roles in developmental, metabolic and signaling pathways. Although vertebrates have one SPP and four SPP-like (SPPL) genes, we found that insect genomes encode one Spp and one SppL. Characterization of the Drosophila...
Autores principales: | Casso, David J., Liu, Songmei, Biehs, Brian, Kornberg, Thomas B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306293/ https://www.ncbi.nlm.nih.gov/pubmed/22439002 http://dx.doi.org/10.1371/journal.pone.0033827 |
Ejemplares similares
-
Physiological functions of SPP/SPPL intramembrane proteases
por: Mentrup, Torben, et al.
Publicado: (2020) -
Dynamic association of the intramembrane proteases SPPL2a/b and their substrates with tetraspanin-enriched microdomains
por: Leinung, Nadja, et al.
Publicado: (2023) -
Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis
por: Mentrup, Torben, et al.
Publicado: (2019) -
The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain
por: Schneppenheim, Janna, et al.
Publicado: (2013) -
The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain
por: Beisner, Daniel R., et al.
Publicado: (2013)