A Unique Modification of the Eukaryotic Initiation Factor 5A Shows the Presence of the Complete Hypusine Pathway in Leishmania donovani

Deoxyhypusine hydroxylase (DOHH) catalyzes the final step in the post-translational synthesis of an unusual amino acid hypusine (N (€)-(4-amino-2-hydroxybutyl) lysine), which is present on only one cellular protein, eukaryotic initiation factor 5A (eIF5A). We present here the molecular and structura...

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Detalles Bibliográficos
Autores principales: Chawla, Bhavna, Kumar, Ravi Ranjan, Tyagi, Nidhi, Subramanian, Gowri, Srinivasan, N., Park, Myung Hee, Madhubala, Rentala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306375/
https://www.ncbi.nlm.nih.gov/pubmed/22438895
http://dx.doi.org/10.1371/journal.pone.0033138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306375/
https://www.ncbi.nlm.nih.gov/pubmed/22438895
http://dx.doi.org/10.1371/journal.pone.0033138

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