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Enhanced Interleukin-1 Activity Contributes to Exercise Intolerance in Patients with Systolic Heart Failure

BACKGROUND: Heart failure (HF) is a complex clinical syndrome characterized by impaired cardiac function and poor exercise tolerance. Enhanced inflammation is associated with worsening outcomes in HF patients and may play a direct role in disease progression. Interleukin-1β (IL-1β) is a pro-inflamma...

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Detalles Bibliográficos
Autores principales:	Van Tassell, Benjamin W., Arena, Ross A., Toldo, Stefano, Mezzaroma, Eleonora, Azam, Tania, Seropian, Ignacio M., Shah, Keyur, Canada, Justin, Voelkel, Norbert F., Dinarello, Charles A., Abbate, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306393/ https://www.ncbi.nlm.nih.gov/pubmed/22438931 http://dx.doi.org/10.1371/journal.pone.0033438

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