Cargando…

Genome-wide structure and organization of eukaryotic pre-initiation complexes

The structural and positional organization of transcription pre-initiation complexes (PICs) across eukaryotic genomes is unknown. We employed ChIP-exo to precisely examine ~6,000 PICs in Saccharomyces. PICs, including RNA polymerase II and general factors TFIIA, -B, -D/TBP, -E, -F, -H, and -K were p...

Descripción completa

Detalles Bibliográficos
Autores principales: Rhee, Ho Sung, Pugh, B. Franklin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306527/
https://www.ncbi.nlm.nih.gov/pubmed/22258509
http://dx.doi.org/10.1038/nature10799