Cargando…

The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis

Malignant astrocytomas are highly aggressive brain tumours with poor prognosis. While a number of structural genomic changes and dysregulation of signalling pathways in gliomas have been described, the identification of biomarkers and druggable targets remains an important task for novel diagnostic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Augustin, Iris, Goidts, Violaine, Bongers, Angelika, Kerr, Grainne, Vollert, Gordon, Radlwimmer, Bernhard, Hartmann, Christian, Herold-Mende, Christel, Reifenberger, Guido, von Deimling, Andreas, Boutros, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306557/ https://www.ncbi.nlm.nih.gov/pubmed/22147553 http://dx.doi.org/10.1002/emmm.201100186

Ejemplares similares

Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis
por: Augustin, Iris, et al.
Publicado: (2013)

The role of Evi/Wntless in exporting Wnt proteins
por: Wolf, Lucie, et al.
Publicado: (2023)

Inhibition of Wntless/GPR177 suppresses gastric tumorigenesis
por: Seo, Jaesung, et al.
Publicado: (2018)

ERAD‐dependent control of the Wnt secretory factor Evi
por: Glaeser, Kathrin, et al.
Publicado: (2018)

Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia
por: Tanaka, Atsushi, et al.
Publicado: (2022)

PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma
por: Phillips, Emma, et al.
Publicado: (2022)

EVI/WLS function is regulated by ubiquitylation and is linked to ER-associated degradation by ERLIN2
por: Wolf, Lucie M., et al.
Publicado: (2021)

Functional characterization of ENPP1 reveals a link between cell cycle progression and stem-like phenotype in glioblastoma
por: Bageritz, Josephine, et al.
Publicado: (2014)

Gpr177 Deficiency Impairs Mammary Development and Prohibits Wnt-Induced Tumorigenesis
por: Maruyama, Eri Ohfuchi, et al.
Publicado: (2013)

PADI4 and tumourigenesis
por: Chang, Xiaotian, et al.
Publicado: (2010)

Suppression of GPR56 expression by pyrrole-imidazole polyamide represents a novel therapeutic drug for AML with high EVI1 expression
por: Saha, Hasi Rani, et al.
Publicado: (2018)

Emerging role for leucine-rich repeat-containing G-protein-coupled receptors LGR5 and LGR4 in cancer stem cells
por: Nakata, Susumu, et al.
Publicado: (2014)

EVI1 in Leukemia and Solid Tumors
por: Liang, Beiyuan, et al.
Publicado: (2020)

Expansive growth of two glioblastoma stem-like cell lines is mediated by bFGF and not by EGF
por: Podergajs, Neza, et al.
Publicado: (2013)

Extent of Resection, MGMT Promoter Methylation Status and Tumor Location Independently Predict Progression-Free Survival in Adult Sporadic Pilocytic Astrocytoma
por: Jungk, Christine, et al.
Publicado: (2019)

Spontaneous Tumourigenesis in Aged Guinea-pigs
por: Lipschutz, A., et al.
Publicado: (1959)

Role of JMJD6 in Breast Tumourigenesis
por: Poulard, Coralie, et al.
Publicado: (2015)

Complement in Tumourigenesis and the Response to Cancer Therapy
por: O’Brien, Rebecca M., et al.
Publicado: (2021)

Intraventricular meningiomas frequently harbor NF2 mutations but lack common genetic alterations in TRAF7, AKT1, SMO, KLF4, PIK3CA, and TERT
por: Jungwirth, Gerhard, et al.
Publicado: (2019)

Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependence
por: Jin, Jay, et al.
Publicado: (2010)

Evi5 is required for Xenopus limb and tail regeneration
por: Yang, Li, et al.
Publicado: (2022)

EVI1-mediated Programming of Normal and Malignant Hematopoiesis
por: Lux, Susanne, et al.
Publicado: (2023)

Toll-Like Receptors, Tissue Injury, and Tumourigenesis
por: Ioannou, Savvas, et al.
Publicado: (2010)

Identification and validation of genes involved in cervical tumourigenesis
por: Rajkumar, Thangarajan, et al.
Publicado: (2011)

The relationship between early embryo development and tumourigenesis
por: Ma, Yanlei, et al.
Publicado: (2010)

Novel In Vitro Assays for the Characterization of EMT in Tumourigenesis
por: Koo, Vincent, et al.
Publicado: (2010)

Paracrine roles of cellular senescence in promoting tumourigenesis
por: Gonzalez-Meljem, Jose Mario, et al.
Publicado: (2018)

Contribution of the KSHV and EBV lytic cycles to tumourigenesis
por: Manners, Oliver, et al.
Publicado: (2018)

RUNX1-EVI1 disrupts lineage determination and the cell cycle by interfering with RUNX1 and EVI1 driven gene regulatory networks
por: Kellaway, Sophie G., et al.
Publicado: (2020)

Focal Chromosomal Copy Number Aberrations Identify CMTM8 and GPR177 as New Candidate Driver Genes in Osteosarcoma
por: Both, Joeri, et al.
Publicado: (2014)

Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models
por: Chen, Su-Ren, et al.
Publicado: (2016)

Prognostic value of the extent of resection in supratentorial WHO grade II astrocytomas stratified for IDH1 mutation status: a single-center volumetric analysis
por: Jungk, Christine, et al.
Publicado: (2016)

High EVI1 Expression due to NRIP1/EVI1 Fusion in Therapy-related Acute Myeloid Leukemia: Description of the First Pediatric Case
por: D’Angiò, Mariella, et al.
Publicado: (2020)

Rapid-CNS(2): rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study
por: Patel, Areeba, et al.
Publicado: (2022)

EVI1 as a Marker for Lymph Node Metastasis in HNSCC
por: Idel, Christian, et al.
Publicado: (2020)

EVI5 is an oncogene that regulates the proliferation and metastasis of NSCLC cells
por: Cai, Tingting, et al.
Publicado: (2020)

EVI1 dysregulation: impact on biology and therapy of myeloid malignancies
por: Birdwell, Christine, et al.
Publicado: (2021)

Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients
por: Jungk, Christine, et al.
Publicado: (2016)

The Hormonal Background of Ovarian Experimental Tumourigenesis in the Guinea-Pig
por: Iglesias, R., et al.
Publicado: (1953)

Tumourigenesis associated with the p53 tumour suppressor gene.
por: Chang, F., et al.
Publicado: (1993)

Cannot write session to /tmp/vufind_sessions/sess_3nrl587h2610el58u61b89jqgj