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The functional role of Notch signaling in HPV-mediated transformation is dose-dependent and linked to AP-1 alterations

BACKGROUND: The role of Notch signaling in HPV-mediated transformation has been a long standing debate, as both tumor suppressive and oncogenic properties have been described. We examined whether the dual findings in literature may be explained by gene dosage effects and determined the relation with...

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Detalles Bibliográficos
Autores principales:	Henken, Florianne E., De-Castro Arce, Johanna, Rösl, Frank, Bosch, Leontien, Meijer, Chris J. L. M., Snijders, Peter J. F., Steenbergen, Renske D. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2012
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306567/ https://www.ncbi.nlm.nih.gov/pubmed/22271085 http://dx.doi.org/10.1007/s13402-011-0062-4

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