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Toll-like receptor polymorphisms and cerebral malaria: TLR2 Δ22 polymorphism is associated with protection from cerebral malaria in a case control study

BACKGROUND: In malaria endemic areas, host genetics influence whether a Plasmodium falciparum-infected child develops uncomplicated or severe malaria. TLR2 has been identified as a receptor for P. falciparum-derived glycosylphosphatidylinositol (GPI), and polymorphisms within the TLR2 gene may affec...

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Detalles Bibliográficos
Autores principales:	Greene, Jennifer A, Sam-Agudu, Nadia, John, Chandy C, Opoka, Robert O, Zimmerman, Peter A, Kazura, James W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306729/ https://www.ncbi.nlm.nih.gov/pubmed/22336003 http://dx.doi.org/10.1186/1475-2875-11-47

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