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Mouse Ficolin B Has an Ability to Form Complexes with Mannose-Binding Lectin-Associated Serine Proteases and Activate Complement through the Lectin Pathway

Ficolins are thought to be pathogen-associated-molecular-pattern-(PAMP-) recognition molecules that function to support innate immunity. Like mannose-binding lectins (MBLs), most mammalian ficolins form complexes with MBL-associated serine proteases (MASPs), leading to complement activation via the...

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Detalles Bibliográficos
Autores principales: Endo, Yuichi, Iwaki, Daisuke, Ishida, Yumi, Takahashi, Minoru, Matsushita, Misao, Fujita, Teizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306798/
https://www.ncbi.nlm.nih.gov/pubmed/22523468
http://dx.doi.org/10.1155/2012/105891