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Changes in Peak Flow Value during Immunotherapy Administration

Nasal allergies are prevalent affecting a large percentage of the population. Not only the upper respiratory tract but the whole body is involved. Allergies produce morbidity (and even occasional mortality) as they can lead to asthma development, and increased number of accidents. Immunotherapy resu...

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Detalles Bibliográficos
Autor principal: Saporta, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306949/
https://www.ncbi.nlm.nih.gov/pubmed/22496703
http://dx.doi.org/10.1155/2012/212867
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author Saporta, Diego
author_facet Saporta, Diego
author_sort Saporta, Diego
collection PubMed
description Nasal allergies are prevalent affecting a large percentage of the population. Not only the upper respiratory tract but the whole body is involved. Allergies produce morbidity (and even occasional mortality) as they can lead to asthma development, and increased number of accidents. Immunotherapy results can be evaluated by following symptom scores, medication use, and objective measurements. Using a Peak Flow Meter (PFM) to evaluate immunotherapy results, it became evident that patients with and without asthma exhibited an improvement in the Peak Flow (PF) value, suggesting that lower airway involvement in allergic patients could be more prevalent than assumed. A consecutive chart review was performed including patients of any age with nasal allergies (with or without asthma) treated with immunotherapy for at least 6 months that had at least 2 complete evaluations. When immunotherapy was successful, most patients exhibited an increase in the PF value regardless of asthma status. A very significant finding was that most allergy sufferers may have lower airway inflammation. The use of the PF value to assess immunotherapy results and the potential failure to diagnose asthma in allergy sufferers are discussed. A better diagnosis of lower airway inflammation could be substantial in the management of these patients.
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spelling pubmed-33069492012-04-11 Changes in Peak Flow Value during Immunotherapy Administration Saporta, Diego J Environ Public Health Clinical Study Nasal allergies are prevalent affecting a large percentage of the population. Not only the upper respiratory tract but the whole body is involved. Allergies produce morbidity (and even occasional mortality) as they can lead to asthma development, and increased number of accidents. Immunotherapy results can be evaluated by following symptom scores, medication use, and objective measurements. Using a Peak Flow Meter (PFM) to evaluate immunotherapy results, it became evident that patients with and without asthma exhibited an improvement in the Peak Flow (PF) value, suggesting that lower airway involvement in allergic patients could be more prevalent than assumed. A consecutive chart review was performed including patients of any age with nasal allergies (with or without asthma) treated with immunotherapy for at least 6 months that had at least 2 complete evaluations. When immunotherapy was successful, most patients exhibited an increase in the PF value regardless of asthma status. A very significant finding was that most allergy sufferers may have lower airway inflammation. The use of the PF value to assess immunotherapy results and the potential failure to diagnose asthma in allergy sufferers are discussed. A better diagnosis of lower airway inflammation could be substantial in the management of these patients. Hindawi Publishing Corporation 2012 2012-02-07 /pmc/articles/PMC3306949/ /pubmed/22496703 http://dx.doi.org/10.1155/2012/212867 Text en Copyright © 2012 Diego Saporta. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Saporta, Diego
Changes in Peak Flow Value during Immunotherapy Administration
title Changes in Peak Flow Value during Immunotherapy Administration
title_full Changes in Peak Flow Value during Immunotherapy Administration
title_fullStr Changes in Peak Flow Value during Immunotherapy Administration
title_full_unstemmed Changes in Peak Flow Value during Immunotherapy Administration
title_short Changes in Peak Flow Value during Immunotherapy Administration
title_sort changes in peak flow value during immunotherapy administration
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306949/
https://www.ncbi.nlm.nih.gov/pubmed/22496703
http://dx.doi.org/10.1155/2012/212867
work_keys_str_mv AT saportadiego changesinpeakflowvalueduringimmunotherapyadministration