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Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy
Tuberculosis (TB) is a leading cause of death globally. Natural history studies show that young children are at particularly high risk of progression to active TB and severe, disseminated disease following infection. Despite this, high-quality regional and global surveillance data on the burden of c...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306957/ https://www.ncbi.nlm.nih.gov/pubmed/22518169 http://dx.doi.org/10.1155/2012/865436 |
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author | Brent, Andrew J. |
author_facet | Brent, Andrew J. |
author_sort | Brent, Andrew J. |
collection | PubMed |
description | Tuberculosis (TB) is a leading cause of death globally. Natural history studies show that young children are at particularly high risk of progression to active TB and severe, disseminated disease following infection. Despite this, high-quality regional and global surveillance data on the burden of childhood TB are lacking. We discuss the unique aspects of TB in children that make diagnosis and therefore surveillance challenging; the limitations of available surveillance data; other data which provide insights into the true burden of childhood TB. Improved surveillance is among the key research priorities identified for childhood TB, but progress to date has been slow. Recent advances in TB diagnostics, and standardized clinical diagnostic guidelines and case definitions, all provide opportunities for new strategies to improve surveillance. Better-quality data on the burden and trends of childhood TB will inform and improve both public health policy and clinical practice. |
format | Online Article Text |
id | pubmed-3306957 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-33069572012-04-19 Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy Brent, Andrew J. J Trop Med Review Article Tuberculosis (TB) is a leading cause of death globally. Natural history studies show that young children are at particularly high risk of progression to active TB and severe, disseminated disease following infection. Despite this, high-quality regional and global surveillance data on the burden of childhood TB are lacking. We discuss the unique aspects of TB in children that make diagnosis and therefore surveillance challenging; the limitations of available surveillance data; other data which provide insights into the true burden of childhood TB. Improved surveillance is among the key research priorities identified for childhood TB, but progress to date has been slow. Recent advances in TB diagnostics, and standardized clinical diagnostic guidelines and case definitions, all provide opportunities for new strategies to improve surveillance. Better-quality data on the burden and trends of childhood TB will inform and improve both public health policy and clinical practice. Hindawi Publishing Corporation 2012 2012-02-14 /pmc/articles/PMC3306957/ /pubmed/22518169 http://dx.doi.org/10.1155/2012/865436 Text en Copyright © 2012 Andrew J. Brent. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Brent, Andrew J. Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy |
title | Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy |
title_full | Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy |
title_fullStr | Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy |
title_full_unstemmed | Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy |
title_short | Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy |
title_sort | childhood tb surveillance: bridging the knowledge gap to inform policy |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306957/ https://www.ncbi.nlm.nih.gov/pubmed/22518169 http://dx.doi.org/10.1155/2012/865436 |
work_keys_str_mv | AT brentandrewj childhoodtbsurveillancebridgingtheknowledgegaptoinformpolicy |