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Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy

Tuberculosis (TB) is a leading cause of death globally. Natural history studies show that young children are at particularly high risk of progression to active TB and severe, disseminated disease following infection. Despite this, high-quality regional and global surveillance data on the burden of c...

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Detalles Bibliográficos
Autor principal: Brent, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306957/
https://www.ncbi.nlm.nih.gov/pubmed/22518169
http://dx.doi.org/10.1155/2012/865436
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author Brent, Andrew J.
author_facet Brent, Andrew J.
author_sort Brent, Andrew J.
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description Tuberculosis (TB) is a leading cause of death globally. Natural history studies show that young children are at particularly high risk of progression to active TB and severe, disseminated disease following infection. Despite this, high-quality regional and global surveillance data on the burden of childhood TB are lacking. We discuss the unique aspects of TB in children that make diagnosis and therefore surveillance challenging; the limitations of available surveillance data; other data which provide insights into the true burden of childhood TB. Improved surveillance is among the key research priorities identified for childhood TB, but progress to date has been slow. Recent advances in TB diagnostics, and standardized clinical diagnostic guidelines and case definitions, all provide opportunities for new strategies to improve surveillance. Better-quality data on the burden and trends of childhood TB will inform and improve both public health policy and clinical practice.
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spelling pubmed-33069572012-04-19 Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy Brent, Andrew J. J Trop Med Review Article Tuberculosis (TB) is a leading cause of death globally. Natural history studies show that young children are at particularly high risk of progression to active TB and severe, disseminated disease following infection. Despite this, high-quality regional and global surveillance data on the burden of childhood TB are lacking. We discuss the unique aspects of TB in children that make diagnosis and therefore surveillance challenging; the limitations of available surveillance data; other data which provide insights into the true burden of childhood TB. Improved surveillance is among the key research priorities identified for childhood TB, but progress to date has been slow. Recent advances in TB diagnostics, and standardized clinical diagnostic guidelines and case definitions, all provide opportunities for new strategies to improve surveillance. Better-quality data on the burden and trends of childhood TB will inform and improve both public health policy and clinical practice. Hindawi Publishing Corporation 2012 2012-02-14 /pmc/articles/PMC3306957/ /pubmed/22518169 http://dx.doi.org/10.1155/2012/865436 Text en Copyright © 2012 Andrew J. Brent. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Brent, Andrew J.
Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy
title Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy
title_full Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy
title_fullStr Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy
title_full_unstemmed Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy
title_short Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy
title_sort childhood tb surveillance: bridging the knowledge gap to inform policy
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306957/
https://www.ncbi.nlm.nih.gov/pubmed/22518169
http://dx.doi.org/10.1155/2012/865436
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