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BALB/c-Fcgr2b(−/−)Pdcd1(−/−) mouse expressing anti-urothelial antibody is a novel model of autoimmune cystitis

We report the impact of anti-urothelial autoantibody (AUAb) on urinary bladder phenotype in BALB/c mice deficient of the FcγRIIb and PD-1. AUAb was present in serum samples from approximately half of the double-knockout (DKO) mice, as detected by immunofluorescence and immunoblots for urothelial pro...

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Detalles Bibliográficos
Autores principales:	Sugino, Yoshio, Nishikawa, Nobuyuki, Yoshimura, Koji, Kuno, Sadako, Hayashi, Yukio, Yoshimura, Naoki, Okazaki, Taku, Kanematsu, Akihiro, Ogawa, Osamu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307042/ https://www.ncbi.nlm.nih.gov/pubmed/22432050 http://dx.doi.org/10.1038/srep00317

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