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Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma
A genome-wide screen for genetic alterations in radiation-induced thymic lymphomas generated from p53+/− and p53−/− mice showed frequent loss of heterozygosity (LOH) on chromosome 6. Fine mapping of these LOH regions revealed three non-overlapping regions, one of which was refined to a 0.2 Mb interv...
Autores principales: | Mao, J-H, Wu, D, Kim, I-J, Kang, H C, Wei, G, Climent, J, Kumar, A, Pelorosso, F G, DelRosario, R, Huang, E J, Balmain, A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307058/ https://www.ncbi.nlm.nih.gov/pubmed/21785465 http://dx.doi.org/10.1038/onc.2011.306 |
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