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The cellular functions of RASSF1A and its inactivation in prostate cancer

Epigenetic events significantly impact the transcriptome of cells and often contribute to the onset and progression of human cancers. RASSF1A (Ras-association domain family 1 isoform A), a well-known tumor suppressor gene, is frequently silenced by epigenetic mechanisms such as promoter hypermethyla...

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Detalles Bibliográficos
Autores principales: Amin, Karishma S., Banerjee, Partha P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307426/
https://www.ncbi.nlm.nih.gov/pubmed/22438769
http://dx.doi.org/10.4103/1477-3163.93000