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Oncocytic lesion of parotid gland: A dilemma for cytopathologists
Oncocytes are epithelial cells with abundant, granular, eosinophilic cytoplasm due to presence of numerous large mitochondria of varied sizes. The presence of oncocytes in salivary glands can occur in a variety of conditions. Here, we present a rare case of a 68 year old male patient who presented w...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307464/ https://www.ncbi.nlm.nih.gov/pubmed/22438628 http://dx.doi.org/10.4103/0970-9371.93236 |
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author | Chakrabarti, Indranil Basu, Amitabha Ghosh, Nilanjana |
author_facet | Chakrabarti, Indranil Basu, Amitabha Ghosh, Nilanjana |
author_sort | Chakrabarti, Indranil |
collection | PubMed |
description | Oncocytes are epithelial cells with abundant, granular, eosinophilic cytoplasm due to presence of numerous large mitochondria of varied sizes. The presence of oncocytes in salivary glands can occur in a variety of conditions. Here, we present a rare case of a 68 year old male patient who presented with a 6 cm diameter swelling in the right parotid region. A fine needle aspiration cytology done from the lesion showed a cellular oncocytic lesion. A possibility of oncocytoma was entertained. Histopathology of the mass showed a rare entity called diffuse hyperplastic oncocytosis. Originally believed to be a metaplastic process, oncocytes can occur in various lesions ranging from hyperplastic conditions to malignant neoplasms. However, diagnosis on cytological smears can be very challenging for the cytopathologist. |
format | Online Article Text |
id | pubmed-3307464 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-33074642012-03-21 Oncocytic lesion of parotid gland: A dilemma for cytopathologists Chakrabarti, Indranil Basu, Amitabha Ghosh, Nilanjana J Cytol Case Report Oncocytes are epithelial cells with abundant, granular, eosinophilic cytoplasm due to presence of numerous large mitochondria of varied sizes. The presence of oncocytes in salivary glands can occur in a variety of conditions. Here, we present a rare case of a 68 year old male patient who presented with a 6 cm diameter swelling in the right parotid region. A fine needle aspiration cytology done from the lesion showed a cellular oncocytic lesion. A possibility of oncocytoma was entertained. Histopathology of the mass showed a rare entity called diffuse hyperplastic oncocytosis. Originally believed to be a metaplastic process, oncocytes can occur in various lesions ranging from hyperplastic conditions to malignant neoplasms. However, diagnosis on cytological smears can be very challenging for the cytopathologist. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3307464/ /pubmed/22438628 http://dx.doi.org/10.4103/0970-9371.93236 Text en Copyright: © Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Chakrabarti, Indranil Basu, Amitabha Ghosh, Nilanjana Oncocytic lesion of parotid gland: A dilemma for cytopathologists |
title | Oncocytic lesion of parotid gland: A dilemma for cytopathologists |
title_full | Oncocytic lesion of parotid gland: A dilemma for cytopathologists |
title_fullStr | Oncocytic lesion of parotid gland: A dilemma for cytopathologists |
title_full_unstemmed | Oncocytic lesion of parotid gland: A dilemma for cytopathologists |
title_short | Oncocytic lesion of parotid gland: A dilemma for cytopathologists |
title_sort | oncocytic lesion of parotid gland: a dilemma for cytopathologists |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307464/ https://www.ncbi.nlm.nih.gov/pubmed/22438628 http://dx.doi.org/10.4103/0970-9371.93236 |
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