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Oncocytic lesion of parotid gland: A dilemma for cytopathologists

Oncocytes are epithelial cells with abundant, granular, eosinophilic cytoplasm due to presence of numerous large mitochondria of varied sizes. The presence of oncocytes in salivary glands can occur in a variety of conditions. Here, we present a rare case of a 68 year old male patient who presented w...

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Autores principales: Chakrabarti, Indranil, Basu, Amitabha, Ghosh, Nilanjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307464/
https://www.ncbi.nlm.nih.gov/pubmed/22438628
http://dx.doi.org/10.4103/0970-9371.93236
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author Chakrabarti, Indranil
Basu, Amitabha
Ghosh, Nilanjana
author_facet Chakrabarti, Indranil
Basu, Amitabha
Ghosh, Nilanjana
author_sort Chakrabarti, Indranil
collection PubMed
description Oncocytes are epithelial cells with abundant, granular, eosinophilic cytoplasm due to presence of numerous large mitochondria of varied sizes. The presence of oncocytes in salivary glands can occur in a variety of conditions. Here, we present a rare case of a 68 year old male patient who presented with a 6 cm diameter swelling in the right parotid region. A fine needle aspiration cytology done from the lesion showed a cellular oncocytic lesion. A possibility of oncocytoma was entertained. Histopathology of the mass showed a rare entity called diffuse hyperplastic oncocytosis. Originally believed to be a metaplastic process, oncocytes can occur in various lesions ranging from hyperplastic conditions to malignant neoplasms. However, diagnosis on cytological smears can be very challenging for the cytopathologist.
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spelling pubmed-33074642012-03-21 Oncocytic lesion of parotid gland: A dilemma for cytopathologists Chakrabarti, Indranil Basu, Amitabha Ghosh, Nilanjana J Cytol Case Report Oncocytes are epithelial cells with abundant, granular, eosinophilic cytoplasm due to presence of numerous large mitochondria of varied sizes. The presence of oncocytes in salivary glands can occur in a variety of conditions. Here, we present a rare case of a 68 year old male patient who presented with a 6 cm diameter swelling in the right parotid region. A fine needle aspiration cytology done from the lesion showed a cellular oncocytic lesion. A possibility of oncocytoma was entertained. Histopathology of the mass showed a rare entity called diffuse hyperplastic oncocytosis. Originally believed to be a metaplastic process, oncocytes can occur in various lesions ranging from hyperplastic conditions to malignant neoplasms. However, diagnosis on cytological smears can be very challenging for the cytopathologist. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3307464/ /pubmed/22438628 http://dx.doi.org/10.4103/0970-9371.93236 Text en Copyright: © Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chakrabarti, Indranil
Basu, Amitabha
Ghosh, Nilanjana
Oncocytic lesion of parotid gland: A dilemma for cytopathologists
title Oncocytic lesion of parotid gland: A dilemma for cytopathologists
title_full Oncocytic lesion of parotid gland: A dilemma for cytopathologists
title_fullStr Oncocytic lesion of parotid gland: A dilemma for cytopathologists
title_full_unstemmed Oncocytic lesion of parotid gland: A dilemma for cytopathologists
title_short Oncocytic lesion of parotid gland: A dilemma for cytopathologists
title_sort oncocytic lesion of parotid gland: a dilemma for cytopathologists
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307464/
https://www.ncbi.nlm.nih.gov/pubmed/22438628
http://dx.doi.org/10.4103/0970-9371.93236
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