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A Chemical Analog of Curcumin as an Improved Inhibitor of Amyloid Abeta Oligomerization

Amyloid-like plaques are characteristic lesions defining the neuropathology of Alzheimer's disease (AD). The size and density of these plaques are closely associated with cognitive decline. To combat this disease, the few therapies that are available rely on drugs that increase neurotransmissio...

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Detalles Bibliográficos
Autores principales: Orlando, Robert A., Gonzales, Amanda M., Royer, Robert E., Deck, Lorraine M., Vander Jagt, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307704/
https://www.ncbi.nlm.nih.gov/pubmed/22442659
http://dx.doi.org/10.1371/journal.pone.0031869