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TLR2 Controls Intestinal Carcinogen Detoxication by CYP1A1

Intestinal cytochrome P450 subclass 1A1 (CYP1A1) contributes to a metabolic “shield” protecting the host from ingested carcinogens such as polycyclic aromatic hydrocarbons (PAH). The expression of CYP1 (including CYP1A2 and CYP1B1) is considered to depend solely on a heterodimeric transcription fact...

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Detalles Bibliográficos
Autores principales: Do, Khoa Nguyen, Fink, Lisbeth Nielsen, Jensen, Thomas Elbenhardt, Gautier, Laurent, Parlesak, Alexandr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307708/
https://www.ncbi.nlm.nih.gov/pubmed/22442665
http://dx.doi.org/10.1371/journal.pone.0032309