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Mutagenesis-Mediated Virus Extinction: Virus-Dependent Effect of Viral Load on Sensitivity to Lethal Defection

BACKGROUND: Lethal mutagenesis is a transition towards virus extinction mediated by enhanced mutation rates during viral genome replication, and it is currently under investigation as a potential new antiviral strategy. Viral load and virus fitness are known to influence virus extinction. Here we ex...

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Detalles Bibliográficos
Autores principales:	Moreno, Héctor, Tejero, Héctor, de la Torre, Juan Carlos, Domingo, Esteban, Martín, Verónica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307711/ https://www.ncbi.nlm.nih.gov/pubmed/22442668 http://dx.doi.org/10.1371/journal.pone.0032550

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