Statistical Inference of In Vivo Properties of Human DNA Methyltransferases from Double-Stranded Methylation Patterns

DNA methyltransferases establish methylation patterns in cells and transmit these patterns over cell generations, thereby influencing each cell's epigenetic states. Three primary DNA methyltransferases have been identified in mammals: DNMT1, DNMT3A and DNMT3B. Extensive in vitro studies have in...

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Detalles Bibliográficos
Autores principales: Fu, Audrey Q., Genereux, Diane P., Stöger, Reinhard, Burden, Alice F., Laird, Charles D., Stephens, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307717/
https://www.ncbi.nlm.nih.gov/pubmed/22442664
http://dx.doi.org/10.1371/journal.pone.0032225

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