Loss of Let-7 Up-Regulates EZH2 in Prostate Cancer Consistent with the Acquisition of Cancer Stem Cell Signatures That Are Attenuated by BR-DIM

The emergence of castrate-resistant prostate cancer (CRPC) contributes to the high mortality of patients diagnosed with prostate cancer (PCa), which in part could be attributed to the existence and the emergence of cancer stem cells (CSCs). Recent studies have shown that deregulated expression of mi...

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Detalles Bibliográficos
Autores principales: Kong, Dejuan, Heath, Elisabeth, Chen, Wei, Cher, Michael L., Powell, Isaac, Heilbrun, Lance, Li, Yiwei, Ali, Shadan, Sethi, Seema, Hassan, Oudai, Hwang, Clara, Gupta, Nilesh, Chitale, Dhananjay, Sakr, Wael A., Menon, Mani, Sarkar, Fazlul H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307758/
https://www.ncbi.nlm.nih.gov/pubmed/22442719
http://dx.doi.org/10.1371/journal.pone.0033729

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