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Identifying New Therapeutic Targets via Modulation of Protein Corona Formation by Engineered Nanoparticles
BACKGROUND: We introduce a promising methodology to identify new therapeutic targets in cancer. Proteins bind to nanoparticles to form a protein corona. We modulate this corona by using surface-engineered nanoparticles, and identify protein composition to provide insight into disease development. ME...
Autores principales: | Arvizo, Rochelle R., Giri, Karuna, Moyano, Daniel, Miranda, Oscar R., Madden, Benjamin, McCormick, Daniel J., Bhattacharya, Resham, Rotello, Vincent M., Kocher, Jean-Pierre, Mukherjee, Priyabrata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307759/ https://www.ncbi.nlm.nih.gov/pubmed/22442705 http://dx.doi.org/10.1371/journal.pone.0033650 |
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