Therapeutic DNA Vaccine Induces Broad T Cell Responses in the Gut and Sustained Protection from Viral Rebound and AIDS in SIV-Infected Rhesus Macaques

Immunotherapies that induce durable immune control of chronic HIV infection may eliminate the need for life-long dependence on drugs. We investigated a DNA vaccine formulated with a novel genetic adjuvant that stimulates immune responses in the blood and gut for the ability to improve therapy in rhe...

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Detalles Bibliográficos
Autores principales: Fuller, Deborah Heydenburg, Rajakumar, Premeela, Che, Jenny W., Narendran, Amithi, Nyaundi, Julia, Michael, Heather, Yager, Eric J., Stagnar, Cristy, Wahlberg, Brendon, Taber, Rachel, Haynes, Joel R., Cook, Fiona C., Ertl, Peter, Tite, John, Amedee, Angela M., Murphey-Corb, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307760/
https://www.ncbi.nlm.nih.gov/pubmed/22442716
http://dx.doi.org/10.1371/journal.pone.0033715

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