Cargando…
A novel hybrid promoter responsive to pathophysiological and pharmacological regulation
The aim of this study was to construct a promoter containing DNA motifs for an endogenous transcription factor associated with inflammation along with motifs for pharmacological regulation factors. We demonstrate in transfected cells that expression of a gene of interest is induced by hypoxic condit...
Autores principales: | Subang, Maria C., Fatah, Rewas, Bright, Carly, Blanco, Patricia, Berenstein, Mariana, Wu, Ying, Podhajcer, Osvaldo L., Winyard, Paul G., Chernajovsky, Yuti, Gould, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308011/ https://www.ncbi.nlm.nih.gov/pubmed/22038171 http://dx.doi.org/10.1007/s00109-011-0826-3 |
Ejemplares similares
-
Gene therapy with an improved doxycycline-regulated plasmid encoding a tumour necrosis factor-alpha inhibitor in experimental arthritis
por: Gould, David, et al.
Publicado: (2007) -
Effects of APC De-Targeting and GAr Modification on the Duration of Luciferase Expression from Plasmid DNA Delivered to Skeletal Muscle
por: Subang, Maria C., et al.
Publicado: (2015) -
Inhibition of established collagen-induced arthritis with a tumour necrosis factor-α inhibitor expressed from a self-contained doxycycline regulated plasmid
por: Gould, David J, et al.
Publicado: (2004) -
Novel delivery methods to achieve immunomodulation
por: Gould, David J, et al.
Publicado: (2007) -
Tumor Associated Stromal Cells Play a Critical Role on the Outcome of the Oncolytic Efficacy of Conditionally Replicative Adenoviruses
por: Lopez, M. Verónica, et al.
Publicado: (2009)