Cargando…
Mutation discovery in mice by whole exome sequencing
We report the development and optimization of reagents for in-solution, hybridization-based capture of the mouse exome. By validating this approach in a multiple inbred strains and in novel mutant strains, we show that whole exome sequencing is a robust approach for discovery of putative mutations,...
Autores principales: | Fairfield, Heather, Gilbert, Griffith J, Barter, Mary, Corrigan, Rebecca R, Curtain, Michelle, Ding, Yueming, D'Ascenzo, Mark, Gerhardt, Daniel J, He, Chao, Huang, Wenhui, Richmond, Todd, Rowe, Lucy, Probst, Frank J, Bergstrom, David E, Murray, Stephen A, Bult, Carol, Richardson, Joel, Kile, Benjamin T, Gut, Ivo, Hager, Jorg, Sigurdsson, Snaevar, Mauceli, Evan, Di Palma, Federica, Lindblad-Toh, Kerstin, Cunningham, Michael L, Cox, Timothy C, Justice, Monica J, Spector, Mona S, Lowe, Scott W, Albert, Thomas, Donahue, Leah Rae, Jeddeloh, Jeffrey, Shendure, Jay, Reinholdt, Laura G |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308049/ https://www.ncbi.nlm.nih.gov/pubmed/21917142 http://dx.doi.org/10.1186/gb-2011-12-9-r86 |
Ejemplares similares
-
Performance of Microarray and Liquid Based Capture Methods for Target Enrichment for Massively Parallel Sequencing and SNP Discovery
por: Kiialainen, Anna, et al.
Publicado: (2011) -
Identification of the Bovine Arachnomelia Mutation by Massively Parallel Sequencing Implicates Sulfite Oxidase (SUOX) in Bone Development
por: Drögemüller, Cord, et al.
Publicado: (2010) -
Grounding grammatical categories: attention bias in hand space influences grammatical congruency judgment of Chinese nominal classifiers
por: Lobben, Marit, et al.
Publicado: (2015) -
A comprehensive classification and nomenclature of carboxyl–carboxyl(ate) supramolecular motifs and related catemers: implications for biomolecular systems
por: D’Ascenzo, Luigi, et al.
Publicado: (2015) -
Microvesicles as Potential Ovarian Cancer Biomarkers
por: Giusti, Ilaria, et al.
Publicado: (2013)