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Mechanisms of B cell autoimmunity in SLE

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that is known to be associated with polyclonal B-cell hyperreactivity. The underlying causes of the diffuse B-cell over-reactivity are unclear, but potential candidates include (a) intrinsic hyper-reactivity leading to polyclonal B-...

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Detalles Bibliográficos
Autores principales: Dörner, Thomas, Giesecke, Claudia, Lipsky, Peter E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308063/
https://www.ncbi.nlm.nih.gov/pubmed/22078750
http://dx.doi.org/10.1186/ar3433