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Human epidermal growth factor receptor bispecific ligand trap RB200: abrogation of collagen-induced arthritis in combination with tumour necrosis factor blockade

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic disease associated with inflammation and destruction of bone and cartilage. Although inhibition of TNFα is widely used to treat RA, a significant number of patients do not respond to TNFα blockade, and therefore there is a compelling need to conti...

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Detalles Bibliográficos
Autores principales: Gompels, Luke L, Malik, Nasser M, Madden, Leigh, Jin, Pei, Feldmann, Marc, Shepard, H Michael, Paleolog, Ewa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308094/
https://www.ncbi.nlm.nih.gov/pubmed/21982514
http://dx.doi.org/10.1186/ar3480