Cargando…
Human epidermal growth factor receptor bispecific ligand trap RB200: abrogation of collagen-induced arthritis in combination with tumour necrosis factor blockade
INTRODUCTION: Rheumatoid arthritis (RA) is a chronic disease associated with inflammation and destruction of bone and cartilage. Although inhibition of TNFα is widely used to treat RA, a significant number of patients do not respond to TNFα blockade, and therefore there is a compelling need to conti...
Autores principales: | Gompels, Luke L, Malik, Nasser M, Madden, Leigh, Jin, Pei, Feldmann, Marc, Shepard, H Michael, Paleolog, Ewa M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308094/ https://www.ncbi.nlm.nih.gov/pubmed/21982514 http://dx.doi.org/10.1186/ar3480 |
Ejemplares similares
-
Selective Inhibition of Membrane Type 1 Matrix Metalloproteinase Abrogates Progression of Experimental Inflammatory Arthritis: Synergy With Tumor Necrosis Factor Blockade
por: Kaneko, Kazuyo, et al.
Publicado: (2016) -
Methionine aminopeptidase-2 blockade reduces chronic collagen-induced arthritis: potential role for angiogenesis inhibition
por: Bainbridge, John, et al.
Publicado: (2007) -
Passive immunization against tumor necrosis factor partially abrogates interleukin 2 toxicity
Publicado: (1989) -
The effect of tumour necrosis factor-α (TNF-α) muteins on human neutrophils in vitro
por: Tchorzewski, H., et al.
Publicado: (1993) -
A window on disease pathogenesis and potential therapeutic strategies: molecular imaging for arthritis
por: Gompels, Luke L, et al.
Publicado: (2011)