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Circulating miR-15b and miR-130b in serum as potential markers for detecting hepatocellular carcinoma: a retrospective cohort study

OBJECTIVE: Serum α-fetoprotein (AFP) is the most commonly used biomarker for screening hepatocellular carcinoma (HCC) but fails to detect about half of the patients. Thus, we investigated if circulating microRNAs (miRNAs) could outperform AFP for HCC detection. DESIGN: A retrospective cohort study....

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Detalles Bibliográficos
Autores principales: Liu, Angela M, Yao, Tzy-Jyun, Wang, Wei, Wong, Kwong-Fai, Lee, Nikki P, Fan, Sheung Tat, Poon, Ronnie T P, Gao, Chunfang, Luk, John M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308260/
https://www.ncbi.nlm.nih.gov/pubmed/22403344
http://dx.doi.org/10.1136/bmjopen-2012-000825