A shift in the balance of vascular endothelial growth factor and connective tissue growth factor by bevacizumab causes the angiofibrotic switch in proliferative diabetic retinopathy

INTRODUCTION: In proliferative diabetic retinopathy (PDR), vascular endothelial growth factor (VEGF) and connective tissue growth factor (CTGF) may cause blindness by neovascularisation followed by fibrosis of the retina. It has previously been shown that a shift in the balance between levels of CTG...

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Detalles Bibliográficos
Autores principales: Van Geest, Rob J, Lesnik-Oberstein, Sarit Y, Tan, H Stevie, Mura, Marco, Goldschmeding, Roel, Van Noorden, Cornelis J F, Klaassen, Ingeborg, Schlingemann, Reinier O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2012
Materias:
Laboratory Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308470/
https://www.ncbi.nlm.nih.gov/pubmed/22289291
http://dx.doi.org/10.1136/bjophthalmol-2011-301005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308470/
https://www.ncbi.nlm.nih.gov/pubmed/22289291
http://dx.doi.org/10.1136/bjophthalmol-2011-301005

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