Balanced Ero1 activation and inactivation establishes ER redox homeostasis

The endoplasmic reticulum (ER) provides an environment optimized for oxidative protein folding through the action of Ero1p, which generates disulfide bonds, and Pdi1p, which receives disulfide bonds from Ero1p and transfers them to substrate proteins. Feedback regulation of Ero1p through reduction a...

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Detalles Bibliográficos
Autores principales: Kim, Sunghwan, Sideris, Dionisia P., Sevier, Carolyn S., Kaiser, Chris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308690/
https://www.ncbi.nlm.nih.gov/pubmed/22412017
http://dx.doi.org/10.1083/jcb.201110090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308690/
https://www.ncbi.nlm.nih.gov/pubmed/22412017
http://dx.doi.org/10.1083/jcb.201110090

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