Cargando…
BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons
Although brain-derived neurotrophic factor (BDNF) regulates numerous and complex biological processes including memory retention, its extremely low levels in the mature central nervous system have greatly complicated attempts to reliably localize it. Using rigorous specificity controls, we found tha...
Autores principales: | Dieni, Sandra, Matsumoto, Tomoya, Dekkers, Martijn, Rauskolb, Stefanie, Ionescu, Mihai S., Deogracias, Ruben, Gundelfinger, Eckart D., Kojima, Masami, Nestel, Sigrun, Frotscher, Michael, Barde, Yves-Alain |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308691/ https://www.ncbi.nlm.nih.gov/pubmed/22412021 http://dx.doi.org/10.1083/jcb.201201038 |
Ejemplares similares
-
Distinct synaptic and neurochemical changes to the granule cell-CA3 projection in Bassoon mutant mice
por: Dieni, Sandra, et al.
Publicado: (2015) -
Organization of Presynaptic Autophagy-Related Processes
por: Gundelfinger, Eckart D., et al.
Publicado: (2022) -
Mechanisms Controlling the Expression and Secretion of BDNF
por: Arévalo, Juan Carlos, et al.
Publicado: (2023) -
The Presynaptic Scaffold Protein Bassoon in Forebrain Excitatory Neurons Mediates Hippocampal Circuit Maturation: Potential Involvement of TrkB Signalling
por: Annamneedi, Anil, et al.
Publicado: (2021) -
BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met
por: Mizui, Toshiyuki, et al.
Publicado: (2015)