Cargando…

Microtubule stability, Golgi organization, and transport flux require dystonin-a2–MAP1B interaction

Loss of function of dystonin cytoskeletal linker proteins causes neurodegeneration in dystonia musculorum (dt) mutant mice. Although much investigation has focused on understanding dt pathology, the diverse cellular functions of dystonin isoforms remain poorly characterized. In this paper, we highli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ryan, Scott D., Bhanot, Kunal, Ferrier, Andrew, De Repentigny, Yves, Chu, Alphonse, Blais, Alexandre, Kothary, Rashmi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308695/ https://www.ncbi.nlm.nih.gov/pubmed/22412020 http://dx.doi.org/10.1083/jcb.201107096

Ejemplares similares

A novel role for the cytoskeletal linker protein dystonin in the maintenance of microtubule stability and the regulation of ER-Golgi transport
por: Ryan, Scott D., et al.
Publicado: (2012)

Neuronal dystonin isoform 2 is a mediator of endoplasmic reticulum structure and function
por: Ryan, Scott D., et al.
Publicado: (2012)

Cytoskeletal Linker Protein Dystonin Is Not Critical to Terminal Oligodendrocyte Differentiation or CNS Myelination
por: Kornfeld, Samantha F., et al.
Publicado: (2016)

HSAN-VI: A spectrum disorder based on dystonin isoform expression
por: Lynch-Godrei, Anisha, et al.
Publicado: (2020)

Motor Unit Abnormalities in Dystonia musculorum Mice
por: De Repentigny, Yves, et al.
Publicado: (2011)

Six1 Regulates MyoD Expression in Adult Muscle Progenitor Cells
por: Liu, Yubing, et al.
Publicado: (2013)

Microtubule Actin Cross-Linking Factor (Macf): A Hybrid of Dystonin and Dystrophin That Can Interact with the Actin and Microtubule Cytoskeletons
por: Leung, Conrad L., et al.
Publicado: (1999)

The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis
por: Jain, Praachi B., et al.
Publicado: (2019)

Hearts of Dystonia musculorum Mice Display Normal Morphological and Histological Features but Show Signs of Cardiac Stress
por: Boyer, Justin G., et al.
Publicado: (2010)

The Proteolipid Protein Promoter Drives Expression outside of the Oligodendrocyte Lineage during Embryonic and Early Postnatal Development
por: Michalski, John-Paul, et al.
Publicado: (2011)

Isoform-specific loss of dystonin causes hereditary motor and sensory neuropathy
por: Motley, William W., et al.
Publicado: (2020)

Concerted effort of centrosomal and Golgi-derived microtubules is required for proper Golgi complex assembly but not for maintenance
por: Vinogradova, Tatiana, et al.
Publicado: (2012)

Microtubule segment stabilization by RASSF1A is required for proper microtubule dynamics and Golgi integrity
por: Arnette, Christopher, et al.
Publicado: (2014)

Poleward Transport of TPX2 in the Mammalian Mitotic Spindle Requires Dynein, Eg5, and Microtubule Flux
por: Ma, Nan, et al.
Publicado: (2010)

Defects in pancreatic development and glucose metabolism in SMN-depleted mice independent of canonical spinal muscular atrophy neuromuscular pathology
por: Bowerman, Melissa, et al.
Publicado: (2014)

Immune dysregulation may contribute to disease pathogenesis in spinal muscular atrophy mice
por: Deguise, Marc-Olivier, et al.
Publicado: (2017)

Epidermolysis Bullosa Simplex With Dystonin Gene Mutation: First Reported Case in Saudi Arabia
por: Al Towijry, Mohammed, et al.
Publicado: (2023)

The organization of Golgi in Drosophila bristles requires microtubule motor protein function and a properly organized microtubule array
por: Melkov, Anna, et al.
Publicado: (2019)

Early onset muscle weakness and disruption of muscle proteins in mouse models of spinal muscular atrophy
por: Boyer, Justin G, et al.
Publicado: (2013)

ER to Golgi Transport: Requirement for P115 at a Pre-Golgi Vtc Stage
por: Alvarez, Cecilia, et al.
Publicado: (1999)

Dystonin modifiers of junctional epidermolysis bullosa and models of epidermolysis bullosa simplex without dystonia musculorum
por: Sproule, Thomas J., et al.
Publicado: (2023)

Associations of elements of the Golgi apparatus with microtubules
Publicado: (1984)

Nucleation and Dynamics of Golgi-derived Microtubules
por: Sanders, Anna A. W. M., et al.
Publicado: (2015)

Microtubule binding by dynactin is required for microtubule organization but not cargo transport
por: Kim, Hwajin, et al.
Publicado: (2007)

Microtubule independent vesiculation of Golgi membranes and the reassembly of vesicles into Golgi stacks
Publicado: (1993)

Differential induction of muscle atrophy pathways in two mouse models of spinal muscular atrophy
por: Deguise, Marc-Olivier, et al.
Publicado: (2016)

More than a bystander: the contributions of intrinsic skeletal muscle defects in motor neuron diseases
por: Boyer, Justin G., et al.
Publicado: (2013)

Suppression of the necroptotic cell death pathways improves survival in Smn(2B/−) mice
por: Chehade, Lucia, et al.
Publicado: (2022)

The Intermediate Filament Protein Peripherin Is the Specific Interaction Partner of Mouse BPAG1-n (Dystonin) in Neurons
por: Leung, Conrad L., et al.
Publicado: (1999)

Isoform-specific mutation in Dystonin-b gene causes late-onset protein aggregate myopathy and cardiomyopathy
por: Yoshioka, Nozomu, et al.
Publicado: (2022)

TGNap1 is required for microtubule-dependent homeostasis of a subpopulation of the plant trans-Golgi network
por: Renna, Luciana, et al.
Publicado: (2018)

Golgi Outposts Locally Regulate Microtubule Orientation in Neurons but Are Not Required for the Overall Polarity of the Dendritic Cytoskeleton
por: Yang, Sihui Z., et al.
Publicado: (2020)

Role of microtubules in the organization and localization of the Golgi apparatus
por: Sandoval, I. V., et al.
Publicado: (1984)

Opposing microtubule motors control motility, morphology and cargo segregation during ER-to-Golgi transport
por: Brown, Anna K., et al.
Publicado: (2014)

Golgi Fragmentation in ALS Motor Neurons. New Mechanisms Targeting Microtubules, Tethers, and Transport Vesicles
por: Haase, Georg, et al.
Publicado: (2015)

Myogenic program dysregulation is contributory to disease pathogenesis in spinal muscular atrophy
por: Boyer, Justin G., et al.
Publicado: (2014)

Regulation of microtubule-based transport by MAP4
por: Semenova, Irina, et al.
Publicado: (2014)

Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport
por: Hirata, Tetsuya, et al.
Publicado: (2015)

Myomegalin is necessary for the formation of centrosomal and Golgi-derived microtubules
por: Roubin, Régine, et al.
Publicado: (2012)

Golgi-derived CLASP-dependent Microtubules Control Golgi Organization and Polarized Trafficking in Motile Cells
por: Miller, Paul M., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_4as7daqstnafq3chvit21689mi