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Recognition of DNA damage by XPC coincides with disruption of the XPC–RAD23 complex

The recognition of helix-distorting deoxyribonucleic acid (DNA) lesions by the global genome nucleotide excision repair subpathway is performed by the XPC–RAD23–CEN2 complex. Although it has been established that Rad23 homologs are essential to protect XPC from proteasomal degradation, it is unclear...

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Detalles Bibliográficos
Autores principales:	Bergink, Steven, Toussaint, Wendy, Luijsterburg, Martijn S., Dinant, Christoffel, Alekseev, Sergey, Hoeijmakers, Jan H.J., Dantuma, Nico P., Houtsmuller, Adriaan B., Vermeulen, Wim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308700/ https://www.ncbi.nlm.nih.gov/pubmed/22431748 http://dx.doi.org/10.1083/jcb.201107050

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