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Ebola GP-Specific Monoclonal Antibodies Protect Mice and Guinea Pigs from Lethal Ebola Virus Infection

Ebola virus (EBOV) causes acute hemorrhagic fever in humans and non-human primates with mortality rates up to 90%. So far there are no effective treatments available. This study evaluates the protective efficacy of 8 monoclonal antibodies (MAbs) against Ebola glycoprotein in mice and guinea pigs. Im...

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Detalles Bibliográficos
Autores principales: Qiu, Xiangguo, Fernando, Lisa, Melito, P. Leno, Audet, Jonathan, Feldmann, Heinz, Kobinger, Gary, Alimonti, Judie B., Jones, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308939/
https://www.ncbi.nlm.nih.gov/pubmed/22448295
http://dx.doi.org/10.1371/journal.pntd.0001575