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Recombinant Vesicular Stomatitis Virus Vaccine Vectors Expressing Filovirus Glycoproteins Lack Neurovirulence in Nonhuman Primates
The filoviruses, Marburg virus and Ebola virus, cause severe hemorrhagic fever with high mortality in humans and nonhuman primates. Among the most promising filovirus vaccines under development is a system based on recombinant vesicular stomatitis virus (rVSV) that expresses an individual filovirus...
Autores principales: | Mire, Chad E., Miller, Andrew D., Carville, Angela, Westmoreland, Susan V., Geisbert, Joan B., Mansfield, Keith G., Feldmann, Heinz, Hensley, Lisa E., Geisbert, Thomas W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308941/ https://www.ncbi.nlm.nih.gov/pubmed/22448291 http://dx.doi.org/10.1371/journal.pntd.0001567 |
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