Small Non-coding RNAs Govern Mammary Gland Tumorigenesis

Small non-coding RNAs include siRNA, miRNA, piRNA and snoRNA. The involvement of miRNAs in the regulation of mammary gland tumorigenesis has been widely studied while the role for other small non-coding RNAs remains unclear. Here we summarize the involvement of miRNA in breast cancer onset and progr...

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Detalles Bibliográficos
Autores principales: Yu, Zuoren, Pestell, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309138/
https://www.ncbi.nlm.nih.gov/pubmed/22382486
http://dx.doi.org/10.1007/s10911-012-9246-4
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author Yu, Zuoren
Pestell, Richard G.
author_facet Yu, Zuoren
Pestell, Richard G.
author_sort Yu, Zuoren
collection PubMed
description Small non-coding RNAs include siRNA, miRNA, piRNA and snoRNA. The involvement of miRNAs in the regulation of mammary gland tumorigenesis has been widely studied while the role for other small non-coding RNAs remains unclear. Here we summarize the involvement of miRNA in breast cancer onset and progression through regulating the cell cycle and cellular proliferation. The regulation of breast cancer stem cells and tumor regeneration by miRNA is reviewed. In addition, the emerging evidence demonstrating the involvement of piRNA and snoRNA in breast cancer is briefly described.
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spelling pubmed-33091382012-03-22 Small Non-coding RNAs Govern Mammary Gland Tumorigenesis Yu, Zuoren Pestell, Richard G. J Mammary Gland Biol Neoplasia Article Small non-coding RNAs include siRNA, miRNA, piRNA and snoRNA. The involvement of miRNAs in the regulation of mammary gland tumorigenesis has been widely studied while the role for other small non-coding RNAs remains unclear. Here we summarize the involvement of miRNA in breast cancer onset and progression through regulating the cell cycle and cellular proliferation. The regulation of breast cancer stem cells and tumor regeneration by miRNA is reviewed. In addition, the emerging evidence demonstrating the involvement of piRNA and snoRNA in breast cancer is briefly described. Springer US 2012-03-01 2012 /pmc/articles/PMC3309138/ /pubmed/22382486 http://dx.doi.org/10.1007/s10911-012-9246-4 Text en © The Author(s) 2012 https://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Article
Yu, Zuoren
Pestell, Richard G.
Small Non-coding RNAs Govern Mammary Gland Tumorigenesis
title Small Non-coding RNAs Govern Mammary Gland Tumorigenesis
title_full Small Non-coding RNAs Govern Mammary Gland Tumorigenesis
title_fullStr Small Non-coding RNAs Govern Mammary Gland Tumorigenesis
title_full_unstemmed Small Non-coding RNAs Govern Mammary Gland Tumorigenesis
title_short Small Non-coding RNAs Govern Mammary Gland Tumorigenesis
title_sort small non-coding rnas govern mammary gland tumorigenesis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309138/
https://www.ncbi.nlm.nih.gov/pubmed/22382486
http://dx.doi.org/10.1007/s10911-012-9246-4
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