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Raphe-mediated signals control the hippocampal response to SRI antidepressants via miR-16

Serotonin reuptake inhibitor (SRI) antidepressants such as fluoxetine (Prozac), promote hippocampal neurogenesis. They also increase the levels of the bcl-2 protein, whose overexpression in transgenic mice enhances adult hippocampal neurogenesis. However, the mechanisms underlying SRI-mediated neuro...

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Detalles Bibliográficos
Autores principales: Launay, J M, Mouillet-Richard, S, Baudry, A, Pietri, M, Kellermann, O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309472/
https://www.ncbi.nlm.nih.gov/pubmed/22833211
http://dx.doi.org/10.1038/tp.2011.54