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Dissociation of accumulated genetic risk and disease severity in patients with schizophrenia
Genotype–phenotype correlations of common monogenic diseases revealed that the degree of deviation of mutant genes from wild-type structure and function often predicts disease onset and severity. In complex disorders such as schizophrenia, the overall genetic risk is still often >50% but genotype...
Autores principales: | Papiol, S, Malzahn, D, Kästner, A, Sperling, S, Begemann, M, Stefansson, H, Bickeböller, H, Nave, K-A, Ehrenreich, H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309490/ https://www.ncbi.nlm.nih.gov/pubmed/22833191 http://dx.doi.org/10.1038/tp.2011.43 |
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