A common and functional mineralocorticoid receptor haplotype enhances optimism and protects against depression in females

Mineralocorticoid (MR) and glucocorticoid receptors (GR) are abundantly expressed in the limbic brain and mediate cortisol effects on the stress-response and behavioral adaptation. Dysregulation of the stress response impairs adaptation and is a risk factor for depression, which is twice as abundant...

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Detalles Bibliográficos
Autores principales: Klok, M D, Giltay, E J, Van der Does, A J W, Geleijnse, J M, Antypa, N, Penninx, B W J H, de Geus, E J C, Willemsen, G, Boomsma, D I, van Leeuwen, N, Zitman, F G, de Kloet, E R, DeRijk, R H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309494/
https://www.ncbi.nlm.nih.gov/pubmed/22832354
http://dx.doi.org/10.1038/tp.2011.59

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