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Hypermethylation of serotonin transporter gene in bipolar disorder detected by epigenome analysis of discordant monozygotic twins
Bipolar disorder (BD) is a severe mental disorder characterized by recurrent episodes of mania and depression. Serotonin transporter (HTT) is a target of antidepressants and is one of the strongest candidate molecules of mood disorder, however, genetic study showed equivocal results. Here, we perfor...
Autores principales: | Sugawara, H, Iwamoto, K, Bundo, M, Ueda, J, Miyauchi, T, Komori, A, Kazuno, A, Adati, N, Kusumi, I, Okazaki, Y, Ishigooka, J, Kojima, T, Kato, T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309511/ https://www.ncbi.nlm.nih.gov/pubmed/22832526 http://dx.doi.org/10.1038/tp.2011.26 |
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