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An Unusual Case of Hashimoto's Thyroiditis with Four Lobed Thyroid Gland

Hashimoto's thyroiditis (HT), an autoimmune disorder, is the most prevalent cause of subclinical or overt hypothyroidism in areas with sufficient iodine intake. The gland is often diffusely enlarged, and the parenchyma is coarsened, hypoechoic, and often hypervascular on ultrasonograpy. Histopa...

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Autores principales: Dar, Rayees Ahmad, Chowdri, Nisar Ahmad, Parray, Fazl Qadir, Wani, Sabiya Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309625/
https://www.ncbi.nlm.nih.gov/pubmed/22454831
http://dx.doi.org/10.4103/1947-2714.93881
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author Dar, Rayees Ahmad
Chowdri, Nisar Ahmad
Parray, Fazl Qadir
Wani, Sabiya Hamid
author_facet Dar, Rayees Ahmad
Chowdri, Nisar Ahmad
Parray, Fazl Qadir
Wani, Sabiya Hamid
author_sort Dar, Rayees Ahmad
collection PubMed
description Hashimoto's thyroiditis (HT), an autoimmune disorder, is the most prevalent cause of subclinical or overt hypothyroidism in areas with sufficient iodine intake. The gland is often diffusely enlarged, and the parenchyma is coarsened, hypoechoic, and often hypervascular on ultrasonograpy. Histopathologic appearance of HT includes lymphocyte aggregates with germinal centers, small thyroid follicles, presence of Hurthle cells, and variable fibrosis. We present a case of a 40-year-old female with suspected follicular neoplasm on fine-needle aspiration cytology of neck swelling. Intraoperatively, thyroid gland was found having four lobes separated from each other. Total thyroidectomy was done and histopathology from all four lobes revealed HT. At present, there is no literature to support the fact that such distorted thyroid anatomy may be due to the underlying disease. If we consider it as thyroid gland anomaly, no such anomaly has been mentioned in the literature till date.
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spelling pubmed-33096252012-03-27 An Unusual Case of Hashimoto's Thyroiditis with Four Lobed Thyroid Gland Dar, Rayees Ahmad Chowdri, Nisar Ahmad Parray, Fazl Qadir Wani, Sabiya Hamid N Am J Med Sci Case Report Hashimoto's thyroiditis (HT), an autoimmune disorder, is the most prevalent cause of subclinical or overt hypothyroidism in areas with sufficient iodine intake. The gland is often diffusely enlarged, and the parenchyma is coarsened, hypoechoic, and often hypervascular on ultrasonograpy. Histopathologic appearance of HT includes lymphocyte aggregates with germinal centers, small thyroid follicles, presence of Hurthle cells, and variable fibrosis. We present a case of a 40-year-old female with suspected follicular neoplasm on fine-needle aspiration cytology of neck swelling. Intraoperatively, thyroid gland was found having four lobes separated from each other. Total thyroidectomy was done and histopathology from all four lobes revealed HT. At present, there is no literature to support the fact that such distorted thyroid anatomy may be due to the underlying disease. If we consider it as thyroid gland anomaly, no such anomaly has been mentioned in the literature till date. Medknow Publications & Media Pvt Ltd 2012-03 /pmc/articles/PMC3309625/ /pubmed/22454831 http://dx.doi.org/10.4103/1947-2714.93881 Text en Copyright: © North American Journal of Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dar, Rayees Ahmad
Chowdri, Nisar Ahmad
Parray, Fazl Qadir
Wani, Sabiya Hamid
An Unusual Case of Hashimoto's Thyroiditis with Four Lobed Thyroid Gland
title An Unusual Case of Hashimoto's Thyroiditis with Four Lobed Thyroid Gland
title_full An Unusual Case of Hashimoto's Thyroiditis with Four Lobed Thyroid Gland
title_fullStr An Unusual Case of Hashimoto's Thyroiditis with Four Lobed Thyroid Gland
title_full_unstemmed An Unusual Case of Hashimoto's Thyroiditis with Four Lobed Thyroid Gland
title_short An Unusual Case of Hashimoto's Thyroiditis with Four Lobed Thyroid Gland
title_sort unusual case of hashimoto's thyroiditis with four lobed thyroid gland
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309625/
https://www.ncbi.nlm.nih.gov/pubmed/22454831
http://dx.doi.org/10.4103/1947-2714.93881
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