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Microencapsulation of Eugenol by Gelatin-Sodium Alginate Complex Coacervation

Present study describes microencapsulation of eugenol using gelatin-sodium alginate complex coacervation. The effects of core to coat ratio and drying method on properties of the eugenol microcapsules were investigated. The eugenol microcapsules were evaluated for surface characteristics, micromerit...

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Detalles Bibliográficos
Autores principales: Shinde, Ujwala, Nagarsenker, Mangal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309654/
https://www.ncbi.nlm.nih.gov/pubmed/22457558
http://dx.doi.org/10.4103/0250-474X.93524
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author Shinde, Ujwala
Nagarsenker, Mangal
author_facet Shinde, Ujwala
Nagarsenker, Mangal
author_sort Shinde, Ujwala
collection PubMed
description Present study describes microencapsulation of eugenol using gelatin-sodium alginate complex coacervation. The effects of core to coat ratio and drying method on properties of the eugenol microcapsules were investigated. The eugenol microcapsules were evaluated for surface characteristics, micromeritic properties, oil loading and encapsulation efficiency. Eugenol microcapsules possessed good flow properties, thus improved handling. The scanning electron photomicrographs showed globular surface of microcapsules prepared with core: coat ratio1:1.The treatment with dehydrating agent isopropanol lead to shrinking of microcapsule wall with cracks on it. The percent oil loading and encapsulation efficiency increased with increase in core: coat ratio whereas treatment with dehydrating agent resulted in reduction in loading and percent encapsulation efficiency of eugenol microcapsules.
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spelling pubmed-33096542012-03-28 Microencapsulation of Eugenol by Gelatin-Sodium Alginate Complex Coacervation Shinde, Ujwala Nagarsenker, Mangal Indian J Pharm Sci Short Communication Present study describes microencapsulation of eugenol using gelatin-sodium alginate complex coacervation. The effects of core to coat ratio and drying method on properties of the eugenol microcapsules were investigated. The eugenol microcapsules were evaluated for surface characteristics, micromeritic properties, oil loading and encapsulation efficiency. Eugenol microcapsules possessed good flow properties, thus improved handling. The scanning electron photomicrographs showed globular surface of microcapsules prepared with core: coat ratio1:1.The treatment with dehydrating agent isopropanol lead to shrinking of microcapsule wall with cracks on it. The percent oil loading and encapsulation efficiency increased with increase in core: coat ratio whereas treatment with dehydrating agent resulted in reduction in loading and percent encapsulation efficiency of eugenol microcapsules. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3309654/ /pubmed/22457558 http://dx.doi.org/10.4103/0250-474X.93524 Text en Copyright: © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Shinde, Ujwala
Nagarsenker, Mangal
Microencapsulation of Eugenol by Gelatin-Sodium Alginate Complex Coacervation
title Microencapsulation of Eugenol by Gelatin-Sodium Alginate Complex Coacervation
title_full Microencapsulation of Eugenol by Gelatin-Sodium Alginate Complex Coacervation
title_fullStr Microencapsulation of Eugenol by Gelatin-Sodium Alginate Complex Coacervation
title_full_unstemmed Microencapsulation of Eugenol by Gelatin-Sodium Alginate Complex Coacervation
title_short Microencapsulation of Eugenol by Gelatin-Sodium Alginate Complex Coacervation
title_sort microencapsulation of eugenol by gelatin-sodium alginate complex coacervation
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309654/
https://www.ncbi.nlm.nih.gov/pubmed/22457558
http://dx.doi.org/10.4103/0250-474X.93524
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