Identification of Risk Factors for Chronic Q Fever, the Netherlands

Since 2007, the Netherlands has experienced a large Q fever outbreak. To identify and quantify risk factors for development of chronic Q fever after Coxiella burnetii infection, we performed a case–control study. Comorbidity, cardiovascular risk factors, medications, and demographic characteristics...

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Detalles Bibliográficos
Autores principales: Kampschreur, Linda M., Dekker, Sandra, Hagenaars, Julia C.J.P., Lestrade, Peter J., Renders, Nicole H.M., de Jager-Leclercq, Monique G.L., Hermans, Mirjam H.A., Groot, Cornelis A.R., Groenwold, Rolf H.H., Hoepelman, Andy I.M., Wever, Peter C., Oosterheert, Jan Jelrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309671/
https://www.ncbi.nlm.nih.gov/pubmed/22469535
http://dx.doi.org/10.3201/eid1804.111478
Descripción
Sumario:Since 2007, the Netherlands has experienced a large Q fever outbreak. To identify and quantify risk factors for development of chronic Q fever after Coxiella burnetii infection, we performed a case–control study. Comorbidity, cardiovascular risk factors, medications, and demographic characteristics from 105 patients with proven (n = 44), probable (n = 28), or possible (n = 33) chronic Q fever were compared with 201 patients who had acute Q fever in 2009 but in whom chronic Q fever did not develop (controls). Independent risk factors for development of proven chronic Q fever were valvular surgery, vascular prosthesis, aneurysm, renal insufficiency, and older age.

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