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Normalisation to Blood Activity Is Required for the Accurate Quantification of Na/I Symporter Ectopic Expression by SPECT/CT in Individual Subjects
The utilisation of the Na/I symporter (NIS) and associated radiotracers as a reporter system for imaging gene expression is now reaching the clinical setting in cancer gene therapy applications. However, a formal assessment of the methodology in terms of normalisation of the data still remains to be...
Autores principales: | Richard-Fiardo, Peggy, Franken, Philippe R., Lamit, Audrey, Marsault, Robert, Guglielmi, Julien, Cambien, Béatrice, Graslin, Fanny, Lindenthal, Sabine, Darcourt, Jacques, Pourcher, Thierry, Vassaux, Georges |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309932/ https://www.ncbi.nlm.nih.gov/pubmed/22470517 http://dx.doi.org/10.1371/journal.pone.0034086 |
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