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Treatment of Mouse Limb Ischemia with an Integrative Hypoxia-Responsive Vector Expressing the Vascular Endothelial Growth Factor Gene
Constitutive vascular endothelial growth factor (VEGF) gene expression systems have been extensively used to treat peripheral arterial diseases, but most of the results have not been satisfactory. In this study, we designed a plasmid vector with a hypoxia-responsive element sequence incorporated int...
Autores principales: | Yasumura, Eduardo Gallatti, Stilhano, Roberta Sessa, Samoto, Vívian Yochiko, Matsumoto, Priscila Keiko, de Carvalho, Leonardo Pinto, Valero Lapchik, Valderez Bastos, Han, Sang Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309937/ https://www.ncbi.nlm.nih.gov/pubmed/22470498 http://dx.doi.org/10.1371/journal.pone.0033944 |
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