Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic

BACKGROUND: Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey o...

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Autores principales: Manirakiza, Alexandre, Boas, Susana Vilas, Beyam, Narcisse, Zadanga, Germain, Konamna, François Xavier, Njuimo, Siméon P, Laganier, Rémi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309964/
https://www.ncbi.nlm.nih.gov/pubmed/22171605
http://dx.doi.org/10.1186/1756-0500-4-543
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author Manirakiza, Alexandre
Boas, Susana Vilas
Beyam, Narcisse
Zadanga, Germain
Konamna, François Xavier
Njuimo, Siméon P
Laganier, Rémi
author_facet Manirakiza, Alexandre
Boas, Susana Vilas
Beyam, Narcisse
Zadanga, Germain
Konamna, François Xavier
Njuimo, Siméon P
Laganier, Rémi
author_sort Manirakiza, Alexandre
collection PubMed
description BACKGROUND: Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region. FINDINGS AND CONCLUSION: The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested.
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spelling pubmed-33099642012-03-23 Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic Manirakiza, Alexandre Boas, Susana Vilas Beyam, Narcisse Zadanga, Germain Konamna, François Xavier Njuimo, Siméon P Laganier, Rémi BMC Res Notes Short Report BACKGROUND: Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region. FINDINGS AND CONCLUSION: The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested. BioMed Central 2011-12-15 /pmc/articles/PMC3309964/ /pubmed/22171605 http://dx.doi.org/10.1186/1756-0500-4-543 Text en Copyright ©2011 Manirakiza et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Report
Manirakiza, Alexandre
Boas, Susana Vilas
Beyam, Narcisse
Zadanga, Germain
Konamna, François Xavier
Njuimo, Siméon P
Laganier, Rémi
Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic
title Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic
title_full Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic
title_fullStr Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic
title_full_unstemmed Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic
title_short Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic
title_sort clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in lobaye, central african republic
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309964/
https://www.ncbi.nlm.nih.gov/pubmed/22171605
http://dx.doi.org/10.1186/1756-0500-4-543
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